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Key takeaways
Generic tizanidine averages about $50 for 30 tablets, but prices can vary by pharmacy and dosage.
Brand-name Zanaflex costs roughly $131 for the same quantity, though generics have been available since 2002.
Using a SingleCare discount may help reduce the price to around $4, or around 90% off the average retail cost.
Tizanidine is a prescription generic drug approved to treat muscle spasms often caused by multiple sclerosis or brain and spinal injuries. The usual retail price averages around $50 for 30 tablets of the 4-mg strength. As a generic medication, it is relatively accessible, although the price can vary depending on the pharmacy and dosage. If cost is still a concern, other generic medications are available that work in a similar way.
RELATED: What is tizanidine?
How much does tizanidine cost without insurance?
Tizanidine prices can vary. It’s a generic prescription medication that’s available as a capsule or tablet, and it’s typically taken multiple times per day. Therefore, 30 tablets may only last around 10 days.
The average cash price for 30 tablets of 4 mg tizanidine is $50. That means the cost per pill is about $1.67, which can equal around $5 per day if the dosage is 4 mg every 8 hours. For a 30-day supply, the costs could be higher, and at a cost of $1.67 per pill, the yearly cost could reach almost $2,000.
Several factors can influence tizanidine prices at different pharmacies:
- Dosage strength (2 mg, 4 mg, or 6 mg)
- Quantity purchased (30, 60, or 90-day supplies)
- Pharmacy location
- Generic vs brand-name versions
- Discount programs and patient assistance options
Discount coupons from SingleCare may help reduce the retail price to around $4. It can also be helpful to compare prices at different pharmacies to get the best price.
How much does brand-name tizanidine cost?
Tizanidine is the generic form of the brand-name drug Zanaflex. Both medications contain the same active ingredient and work the same way to treat muscle spasticity. The generic version has been available since 2002 and is widely available. However, the brand-name drug is still available, albeit at a higher price in most cases. The average cost of 30, 4 mg Zanaflex tablets is around $131.
Compare Zanaflex (tizanidine) prices to related drugs |
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|---|---|---|---|
| Drug name | Price without insurance | SingleCare price | Savings options |
| Zanaflex | $131 per 30, 4 mg tablets | $4 per 30, 4 mg tablets of generic Zanaflex at Kroger | See latest prices |
| Generic Zanaflex (tizanidine) | $50 per 30, 4 mg tablets | $4 per 30, 4 mg tablets of generic Zanaflex at Kroger | See latest prices |
| Flexeril (cyclobenzaprine) | $54 per 30, 10 mg tablets | $8 per 30, 10 mg tablets of generic Flexeril at Kroger | See latest prices |
| Robaxin (methocarbamol)
|
$25 per 1, 10 mL of 1000 mg/10 mL vial | $5 per 30, 500 mg tablets of generic Robaxin at Kroger | See latest prices |
| Skelaxin (metaxalone) | $189 per 30, 800 mg tablets | $25 per 30, 800 mg tablets of generic Metaxalone at Kroger | See latest prices |
| Lorzone (chlorzoxazone) | $46 per 30, 500 mg tablets | $12 per 30, 500 mg tablets of generic Lorzone at Kroger | See latest prices |
| Fleqsuvy (baclofen) | $907 per 1, 120 mL of 25 mg/5 mL bottle | $159 per 1, 120 mL of 25 mg/5 mL bottle of generic Fleqsuvy at CVS Pharmacy | See latest prices |
| Dantrium (dantrolene) | $128 per 90, 25 mg capsules | $35 per 90, 25 mg capsules of generic Dantrium at CVS Pharmacy | See latest prices |
Prescription drug prices often change. These are the most accurate medication prices at the time of publishing in ZIP code 23666 as of 12/03/2025. The listed price without insurance references the price of brand-name drugs (unless otherwise specified). The listed SingleCare price references the price of generic drugs if available.
RELATED: Tizanidine alternatives: What can I take instead of tizanidine?
Save up to 80% on Tizanidine with SingleCare
Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.
Tizanidine costs by dose
The quantity and strength of tizanidine tablets will affect the overall cost of the medication. Higher doses and larger quantities often cost more without insurance coverage. Tizanidine comes as an oral tablet and capsule in different strengths, which can be taken multiple times per day. Those who take fewer tablets per day may see lower costs than those who take more.
Compare tizanidine prices by strength |
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|---|---|---|
| (per 30 tablets or capsules) | ||
| Strength | SingleCare price of brand-name tizanidine | SingleCare price of generic tizanidine |
| 2 mg of tizanidine tablets | N/A | $9 at Kroger |
| 4 mg of tizanidine tablets | $107 | $4 at Kroger |
| 2 mg of tizanidine capsules | N/A | $10 at Kroger |
| 4 mg of tizanidine capsules | N/A | $8 at Kroger |
| 6 mg of tizanidine capsules | N/A | $15 at Kroger |
| See our lowest price for tizanidine without insurance | ||
Prescription drug prices often change. These are the most accurate medication prices at the time of publishing in zip code 23666. Click the link under “See our lowest price” to see the latest drug prices.
Is tizanidine covered by insurance?
Yes, tizanidine is usually covered by most insurance plans, including Medicare Part D plans, in the United States. Insurance plans generally prefer to cover the generic version rather than the brand-name drug, with the prices varying between different plans.
Even with insurance, patients may still have out-of-pocket costs in the form of copays or coinsurance amounts. These costs can vary depending on an individual’s plan and whether they’ve met their deductible.
Patients should check with their specific insurance provider to verify the details of their coverage. Some plans may require prior authorization or have quantity limits.
How to get tizanidine without insurance
Paying for prescription drugs can be difficult for some people, especially without insurance. However, there are various ways to avoid paying the full retail price of a medication. Manufacturer coupons and patient assistance programs may be available, but many people might not qualify for them. The following options may be helpful for those looking to save without insurance.
1. Using a SingleCare discount card
A SingleCare discount card may be a convenient way to save on prescription drugs like tizanidine without insurance. Without insurance, tizanidine typically costs $50 for 30 tablets. With a SingleCare coupon, patients may pay just $4 for the same quantity. That’s over 90% in savings off the regular cash price. The discount card is free and doesn’t require membership fees or eligibility requirements.
2. Comparing pharmacy prices
Not every pharmacy may have the same price for tizanidine tablets and capsules. The price can change, especially with online pharmacies and retail chains offering competitive cash prices for people without insurance. Since pharmacy location is a big factor in price, patients could save quite a bit by just checking out other pharmacies.
3. Switching to an alternative
If cost is still an obstacle with tizanidine, other options are available. A muscle relaxant like Flexeril (cyclobenzaprine), Robaxin (methocarbamol), Skelaxin (metaxalone), or Baclofen (baclofen) could work just as well with relatively low-cost generics available. While these medications can help manage muscle spasms, prices and potential side effects can vary. It’s best to visit a doctor or healthcare provider for medical advice and more information on the most effective treatment option.
The SingleCare prices in this article are the most accurate at the time of publishing in ZIP code 23666 as of 12/03/2025. Prices vary by pharmacy. Visit our Tizanidine coupon page for updated prices near you.
- Teva announces approval of tizanidine HCl tablets, Teva Pharmaceutical Industries Ltd (2002)
- Zanaflex highlights of prescribing information, U.S. Food and Drug Administration (2024)
- Medicare Part D plans rarely cover brand-name drugs when generics are available, Health Affairs (2022)