Key takeaways
Addyi is one of only two prescription medications FDA-approved to treat hypoactive sexual dysfunction disorder in pre-menopausal women and is the only medicine approved for this disorder in post-menopausal women under the age of 65.
As a brand-name drug, Addyi costs over $2,000 per month and is often not covered by health insurance.
Using a SingleCare Addyi coupon and comparing pharmacy prices are two options for reducing the out-of-pocket cost of Addyi.
Addyi (flibanserin) is a prescription medication used to treat low sexual desire (hypoactive sexual desire disorder or HSDD) in pre-menopausal women and post-menopausal women under age 65. Without insurance, Addyi costs $2,086 for 30, 100 mg tablets. Although there are no generic or over-the-counter alternatives, there are several ways to make an Addyi prescription more affordable.
How much does Addyi cost without insurance?
Addyi’s average cash price is $2,086 for 30, 100 mg tablets for people without insurance coverage. Each tablet costs about $70.
Addyi must be taken daily, possibly for eight weeks, to become effective. Much like an antidepressant, the active ingredient in Addyi changes the chemical balance of neurotransmitters in the central nervous system. It may take four to eight weeks for its effects to become noticeable and longer to reach its maximum benefits. Therapy could continue indefinitely. This means the cost of Addyi could be approximately $25,000 annually.
Unlike erectile dysfunction treatment for men, such as Viagra, pharmacological options specific to the management of low libido in women are limited. Besides Addyi, Vyleesi (bremelanotide) is the only other drug FDA-approved to treat low sex drive in pre-menopausal women. It’s administered as an injection and taken as-needed 45 minutes before sexual encounters. The cash price for Vyleesi is $1,411 for four doses, with a maximum of eight doses recommended per month.
Doctors sometimes use drugs off-label to treat HSDD, including the antidepressant bupropion or the male sex hormone testosterone. Both are effective but can have worrisome side effects. The only other pharmacological treatment options are over-the-counter supplements, which are not proven therapies.
A variety of other treatment options are available to improve low libido, including lifestyle modifications, cognitive behavioral therapy, counseling, relationship therapy, or other types of psychotherapy. An underlying medical condition may be causing the symptoms. Possible causes include low estrogen levels, underactive thyroid, high prolactin levels, diabetes, depression, substance use disorder, or other mental health conditions. Treating the underlying condition may improve sexual interest and activity.
Sexual performance may also be affected by current medications, so get medical advice from a healthcare professional who can help review prescription drugs and herbal supplements that may be contributing to low libido. For instance, many antidepressants cause sexual dysfunction, including SSRIs, SNRIs, and tricyclic antidepressants. Prescribers could lower the dose or switch to antidepressants that either do not cause sexual dysfunction or have a less severe effect on libido. Options include bupropion, mirtazapine, nefazodone, vilazodone, and Trintellix (vortioxetine).
How much does generic Addyi cost?
Addyi is currently only available as a brand-name drug. A generic version of Addyi will not be available until 2028 at the earliest.
Compare Addyi prices to related drugs |
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|---|---|---|---|
| Drug name | Price without insurance of brand-name drug | SingleCare price | Savings options |
| Addyi (flibanserin) | $2,086 for 30, 100 mg tablets | $1,957 for 30, 100 mg tablets of brand-name Addyi at Kroger | See latest prices |
| Vyleesi (bremelanotide acetate) | $1,411 for 4, 4 mL of 1.75 mg/0.3 mL pens | $972 for 4, 4 mL of 1.75 mg/0.3 mL pens of brand-name Vyleesi at Walgreens | See latest prices |
| Wellbutrin SR
(bupropion sustained-release) |
$566 for 60, 150 mg tablets | $6 for 60, 150 mg tablets of generic bupropion SR at Kroger | See latest prices |
Is Addyi covered by insurance?
Addyi is not usually covered by commercial health insurance, but some plans may cover it, such as Sentara and UnitedHealthcare. Medicare plans generally do not cover Addyi because the Food and Drug Administration has not approved it for use in women over age 65. Medicaid coverage will vary by state.
Addyi copays will vary by plan, but insurance plans generally place Addyi in higher copay tiers, including non-preferred or non-formulary tiers. If the drug is on your plan’s formulary, your healthcare provider may need to obtain prior authorization. The Addyi Savings card can reduce the copay, but it’s only valid at a single mail-order pharmacy.
How to get Addyi covered by insurance
Insurance companies will likely turn down an Addyi prescription because they don’t cover it. The only recourse is to file a formulary exception. The first step is to speak with an insurance representative to determine which paperwork the prescriber must submit.
If Addyi is on the formulary, it could still be turned down because not all diagnostic criteria are met or because prior authorization is required. Meeting the diagnostic criteria is important. Even the terminology for the condition has changed from HSDD to female sexual interest and arousal disorder (FSIAD). This diagnosis includes lack of sexual desire, lack of physical arousal, or both.
After being diagnosed with HSDD or FSIAD, to meet the specific FDA indication for Addyi use, low sexual desire in a woman must be acquired (experienced after previously having normal sexual interest), be generalized (occurs no matter what the circumstances), cause distress, and not be secondary to physical problems, mental health problems, drugs, or relationship issues. Those requirements are difficult to demonstrate and can only be confirmed with a thorough history and lab tests. The insurance provider may have additional criteria that need to be met. For perspective, see UnitedHealthcare’s requirements here.
Prior authorization involves the prescriber providing evidence that all the requirements for treatment and coverage are met before the drug is authorized.
Refills may be denied if the medicine doesn’t work or if quantity limits are exceeded.
How to get Addyi without insurance
Premium-priced medications like Addyi can be challenging to pay for month after month. Fortunately, there are alternatives to paying the full price of your Addyi prescription without insurance. Sprout Pharmaceuticals, the manufacturer, does not currently offer manufacturer coupons or a patient assistance program for uninsured individuals. Here are some more dependable ways to save money on Addyi:
1. Use a SingleCare discount card
A SingleCare discount card may help reduce the Addyi price at Kroger from $2,086 per month to as low as $1,957, a savings of around $100. The savings could add up to more than $1,200 in a year. Visit SingleCare’s Addyi coupon page to find the best price. SingleCare is free to use and available to everyone. Registered members can save even more, and it’s fast and free to join.
Save up to 80% on Addyi with SingleCare
Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.
2. Compare prices at multiple pharmacies
Prices for Addyi vary from pharmacy to pharmacy. Scope out different pharmacies to see where you can get the lowest prices and the most savings. Entering your zip code on the SingleCare Addyi page will let you see prices from a host of local pharmacies. Pharmacies may also offer discounts or savings, so make sure to speak to your pharmacist.
3. Try non-pharmacologic approaches
If cost is a barrier to Addyi, ask your healthcare provider about non-pharmacological alternatives like psychotherapy, sexual counseling, or relationship therapy to better address potential causes of low libido.
4. Ask the prescriber about underlying conditions
The prescriber will try to identify possible underlying conditions that cause low libido, including low estrogen levels, other hormone disorders, mental health problems, diabetes, and liver disease. Addyi works by changing brain chemistry, not by fixing any other underlying cause. If it hasn’t been tried, talk to the prescriber about testing hormone levels and assessing for mental health or physical problems.
5. Ask about supplements or alternative treatments
Alternative treatments may also be effective, but they are not thoroughly tested or FDA-approved. A hormone-free dietary supplement known as Ristela has been used to improve sexual health in women. Always ask your healthcare provider before starting supplements. Other alternative treatments, such as mindfulness exercises or meditation, can address some of the factors that contribute to low sexual desire.
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The SingleCare prices in this article are the most accurate at the time of publishing in ZIP code 23666 as of Sep. 1, 2026. Prices vary by pharmacy. Visit our coupon page for updated drug prices at pharmacies near you.
- Addyi flibanserin tablet prescribing information, DailyMed (NIH National Library of Medicine) (2025)
- Vyleesi bremelanotide injection prescribing information, DailyMed (NIH National Library of Medicine) (2025)
- Female sexual interest and arousal disorder, StatPearls (2024)
- Low sex drive in women—symptoms and causes, Mayo Clinic (2024)
- The sexual dysfunction in women with thyroid disorders: a meta-analysis, BMC Endocrine Disorders (2024)
- Antidepressants: Which cause the fewest side effects?, Mayo Clinic (2024)
- Antidepressant-induced female sexual dysfunction, Mayo Clinic Proceedings (2019)
- Addyi drug patent profile, Drug Patent Watch (2026)
- Sentara Individual and Family Plans Prescription Drugs Formulary, Sentara Health Plans (2026)
- United Healthcare Addyi coverage criteria, United Healthcare (2026)
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