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Key takeaways
Repatha (evolocumab) is a brand-name injectable prescription medication used for cardiovascular risk reduction, high cholesterol, heterozygous familial hypercholesterolemia (HeFH), and homozygous familial hypercholesterolemia (HoFH).
The cost of Repatha depends on the dosage and quantity prescribed as well as the pharmacy where you fill your prescription. The average monthly cost of Repatha without insurance for two SureClick injectors is $763.
Many commercial insurance companies, Medicare prescription plans, and Medicaid plans cover Repatha, but drug coverage details and out-of-pocket costs will vary. You can check with your specific plan for more information on coverage and costs.
Repatha is a brand-name prescription medication made by the pharmaceutical company Amgen. Repatha contains the active ingredient evolocumab, but no generic is available at this time. Repatha is classified as a PCSK9 inhibitor. It is approved by the Food and Drug Administration (FDA) to reduce the risk of major adverse cardiovascular events in high-risk adults. These events include heart attack, stroke, unstable angina (chest pain) that requires a hospital stay, coronary revascularization (a procedure that restores blood flow to the heart), and death from heart disease. Repatha is also used along with diet and exercise to reduce low-density lipoprotein cholesterol levels (LDL-C) in the following individuals:
- Adults with hypercholesterolemia
- Adults and children 10 years and older with a genetic condition called heterozygous familial hypercholesterolemia (HeFH)
- Adults and children 10 years and older with a genetic condition called homozygous familial hypercholesterolemia (HoFH)
How much does Repatha cost per month?
Your cost will depend on several factors, such as the formulation prescribed, the pharmacy where you fill your prescription, and the quantity dosage prescribed:
- For cardiovascular risk reduction, hypercholesterolemia, or HeFH, the typical dose is either 140 mg injected every two weeks or 420 mg injected once per month.
- For HoFH, the typical dose is 420 mg injected once per month, but some people may need a higher dose of 420 mg every two weeks.
Repatha is available in two formulations, each containing 140 mg per single-use device:
The Repatha Pushtronex system, which delivered 420 mg in an on-body infusion system, has been discontinued, so people who need a 420 mg dose will require three consecutive 140 mg injections.
People with latex allergies should ensure the version of Repatha they receive does not contain latex. This information should be on the label, and you can double-check with your pharmacist.
Cost of Repatha SureClick per month
Without insurance, the average monthly cost of Repatha SureClick pens is $763 for two, 140 mg/mL pens. With a SingleCare coupon for Repatha SureClick, you can pay $462 for this prescription, depending on your choice of pharmacy.
Cost of Repatha prefilled syringes
The average cost per month of Repatha prefilled syringes is about $794 for two, 140 mg/mL syringes. However, if you use a free SingleCare coupon for Repatha syringes, you can pay as low as $462 per month. The following tables show the dosage and prices for the common doses of Repatha SureClick autoinjectors and prefilled syringes.
Repatha SureClick cost per month by dosage |
|||
|---|---|---|---|
| Dosage prescribed | Cost without insurance per month* | SingleCare cost per month* | How to save |
| 420 mg injected once monthly | $1,137 for 3, 140mg/ml SureClick autoinjectors | $692 for 3, SureClick autoinjectors | Get coupon |
| 140 mg injected every two weeks | $763 for 2, 140mg/ml SureClick autoinjectors | $462 for 2, SureClick autoinjectors | Get coupon |
Repatha prefilled syringe cost per month by dosage |
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|---|---|---|---|
| Dosage prescribed | Cost without insurance per month* | SingleCare cost per month* | How to save |
| 420 mg injected once monthly | $1,033 for 3, 140mg/ml single-dose prefilled syringes | $692 for 3, single-dose prefilled syringes | Get coupon |
| 140 mg injected every two weeks | $794 for 2, 140mg/ml single-dose prefilled syringes | $462 for 2, single-dose prefilled syringes | Get coupon |
Prescription drug prices often change. These are the most accurate medication prices at the time of publishing in ZIP code 23666 as of Dec. 9, 2025. The listed price without insurance references the price of brand-name drugs (unless otherwise specified). The listed SingleCare price references the price of generic drugs if available.
Is Repatha covered by insurance?
According to Amgen, Repatha’s manufacturer, about 98% of patients with commercial health insurance (such as through an employer) have coverage for Repatha.
Additionally, approximately 97% of people with Medicaid are covered for this prescription, as well as about 84% of those with prescription drug coverage under Medicare Part D or a Medicare Advantage plan.
Other individual considerations may play a role, too, such as your deductible and coinsurance. To find out for sure whether your specific drug plan covers Repatha, and what your cost would be, you can:
- Call the member services department for your plan and ask about Repatha coverage and out-of-pocket costs.
- Log in to your health plan’s online account and check the most recent formulary (list of covered medications and payment tiers).
- Have your healthcare provider send a prescription to your preferred pharmacy. Your pharmacy staff can process the prescription electronically and tell you if it is covered, needs prior authorization, or is not covered at all.
How to get Repatha without insurance
It can be difficult for the average person to pay for a brand-name medication like Repatha without insurance. The good news is that there are some alternatives to paying full price for your Repatha prescription without insurance. Programs like Repatha copay cards, free trial offers, and patient assistance programs are sometimes available, but eligibility requirements vary, and not everyone can use these discounts. Here are some more dependable ways to save money on Repatha without insurance:
- Take advantage of SingleCare discounts. SingleCare’s prescription discount program is free and easy to use. You can use SingleCare at over 35,000 pharmacies, on your initial prescription and refills, too. The retail price of Repatha (two 140 mg/ml SureClick autoinjector pens) is about $763, but with your free SingleCare discount card, you could pay as little as $462, saving almost $300 each month.
- Compare pharmacy prices. There is no generic version of Repatha, but you can save money on this brand-name drug by checking the price at different pharmacies near you. Prices can vary significantly among pharmacies, and SingleCare makes it easy to compare local prices online or by using the SingleCare app. What’s more, some pharmacies may offer additional savings when you purchase a three-month supply up front, so you can inquire about the price of a one-month supply versus a three-month supply.
- Ask for samples. Ask your healthcare provider if they have any samples of Repatha. Although free samples are not a permanent cost-saving solution, you could save a significant amount of money by obtaining a few weeks (or even months) worth of medicine from your healthcare provider.
- Get advice from your healthcare team. Different cities and towns offer programs that can help you save on your prescription medications. Ask your healthcare provider, pharmacist, or health department whether they know of any local resources that can help you save money on your medication. If your Repatha cost is still too high despite trying these solutions, you can also ask your healthcare provider for information and medical advice about Repatha alternatives.
- Repatha, DailyMed (2025)
- Paying for Repatha, Amgen
- Important notice for patients: Discontinuation of Repatha (evolocumab) Pushtronex system (single-dose on-body infusor with prefilled cartridge) and for latex allergy patients, the addition of prefilled syringe not made with natural rubber latex available January 2025, followed by SureClick autoinjector not made with natural rubber latex available April 2025, Amgen (2025)