What is Myrbetriq: Uses, Warnings & Interactions
Myrbetriq is a brand-name prescription drug that treats overactive bladder symptoms in both adults and children. Its active ingredient is mirabegron, a drug that relaxes the major bladder muscle that squeezes out urine. Healthcare professionals often prescribe Myribetriq along with another drug that relaxes bladder muscles called VESIcare (solifenacin succinate). Doses are taken once daily at the same time every day without regard to food.
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Myrbetriq overview
BRAND NAMES:
Myrbetriq
Generic Names:
Myrbetriq
Uses:
Treats symptoms of an overactive bladder in adults and children.
Therapeutic Classes:
Beta-3 agonist, urinary enuresis agent, genitourinary agent
Forms:
Extended-release tablet, extended-release oral suspension
How it’s taken:
By mouth
What is Myrbetriq used for?
Myrbetriq relieves urinary incontinence, urinary urges, and urinary frequency in adults with overactive bladder syndrome (OAB) and children with neurogenic detrusor overactivity (NDO).
What form(s) does Myrbetriq come in
Extended-release tablets
25 mg
50 mg
Extended-release oral suspension
8 mg/mL
What are common Myrbetriq doses?
For overactive bladder in adults: 25–50 mg tablets taken once daily
For neurogenic detrusor overactivity in children:
Weighing more than 35 kg: 25–50 mg tablets OR 6–10 mL (48–80 mg) oral suspension taken once daily
In children weighing between 22–34 kg: 4–8 mL (32–64 mg) oral suspension taken once daily
In children weighing between 11–21 kg: 3–6 mL (24–48 mg) oral suspension taken once daily
Common Myrbetriq prescriptions
Myrbetriq
25mg 24-hour extended-release tabletMyrbetriq
50mg 24-hour extended-release tabletMyrbetriq
100ml of 8mg/ml bottleMyrbetriq
7 tablets extended release 24 hour disp packMyrbetriq
25mg tabletMyrbetriq
50mg tabletMyrbetriq
25mg tablet extended release 24 hourMyrbetriq
50mg tablet extended release 24 hour
How to take Myrbetriq
Take Myrbetriq as directed.
Please read the Patient Information sheet that comes with this medicine.
The clinician may also prescribe solifenacin tablets. Take both medicines together at the same time every day.
Myrbetriq can be taken with or without food.
Always administer Myrbetriq with food when dosing a child.
How to take Myrbetriq tablets:
Swallow the Myrbetriq tablet whole with a glass of water. Do not crush, break, or chew the tablet.
Store Myrbetriq tablets at room temperature.
How to take or administer Myrbetriq oral suspension:
Shake the bottle vigorously for one minute before measuring a dose.
Allow the bottle to sit for one to two minutes after shaking it to allow the foam to settle.
Measure and give the dose within one hour of shaking the bottle.
Only use the calibrated oral syringe or other dosing device provided with the medicine to measure out the dose. Do not use kitchen measuring spoons or tableware.
Wash the dosing device with water and mild detergent. Rinse. Let air dry.
Store Myrbetriq oral suspension at room temperature.
Throw out the bottle and any remaining medicine 28 days after the pharmacist has prepared the suspension.
What to do if you miss a dose of Myrbetriq
Take a missed dose as soon as it’s remembered.
However, if a dose is missed by more than 12 hours, do not take the missed dose.
Take the next dose at its regular time.
Myrbetriq contraindications
This medicine is not right for everyone.
Do not use it if you have had an allergic reaction to mirabegron.
Myrbetriq warnings
The prescriber may need regular visits and lab tests to check on the effects of this medicine. Children taking Myrbetriq will require regular blood pressure checks. Keep all appointments.
Tell other healthcare professionals who treat you that you are taking Myrbetriq.
Before starting Myrbetriq, tell the doctor if you are pregnant, breastfeeding, or if you have:
Kidney problems
Liver problems
High blood pressure
Trouble urinating or a weak urine stream
Myrbetriq can cause serious problems, including:
Urinary retention
High blood pressure
An allergic reaction involving severe swelling and possible airway closure (angioedema)
Myrbetriq interactions
There are only a few major Myrbetriq drug interactions, but Myrbetriq might increase the risk of side effects caused by some drugs.
Tell the prescribing healthcare provider about all the prescription drugs, over-the-counter medications, and supplements you take before starting Myrbetriq, particularly:
Other drugs that treat overactive bladder called anticholinergic drugs
The heart drug digoxin.
Tell other healthcare providers you are using this medicine before they prescribe new medications.
Myrbetriq side effects
Serious side effects
Talk to a doctor if you notice any signs or symptoms of a possible serious side effect, including:
Decrease in how much or how often you urinate, difficulty urinating
Increased blood pressure
Allergic reaction: Itching, rash, hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Less serious side effects
Nasal congestion, sore throat
Urinary tract infection
Headache
Constipation
Find more information about Myrbetriq side effects here.
Sources:
Myrbetriq drug summary, Prescriber’s Digital Reference (PDR)
Myrbetriq mirabegron tablet/mirabegron granules for suspension prescribing information, DailyMed (NIH National Library of Medicine)
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