Key takeaways
Tremfya has a list price of $14,566.44 per dose, according to the manufacturer, but the amount someone pays without insurance can vary by dosage form, dose, and pharmacy.
Free SingleCare coupons can be used to save thousands of dollars on every Tremfya refill.
Less expensive biologic drugs and non-biologic alternatives may be viable options worth discussing with one’s healthcare team.
Tremfya (guselkumab) is a brand-name injectable medication that is prescribed to combat inflammation in the setting of severe plaque psoriasis, psoriatic arthritis, and ulcerative colitis. It is a biologic drug, more specifically a monoclonal antibody, that binds to the inflammatory mediator interleukin-23 (IL-23) to stop the autoimmune cascade fueling these health conditions. Like most biologic drugs, Tremfya carries a hefty price tag. Those hardest hit are people without health insurance. We will examine its expense and ways to save.
Is Tremfya covered by insurance?
If you have insurance, the best way to know if you have coverage for Tremfya is to check your insurance provider’s formulary. Insurance coverage will vary from plan to plan. For example, Humana Medicare’s formulary lists Tremfya as not covered, while Aetna’s Standard Plan labels the drug as a preferred specialty product. Preferred status often means a lower copay for meds that are covered compared to non-preferred options. These details will determine how much you have to pay out-of-pocket for Tremfya.
How much does Tremfya cost without insurance?
Tremfya can be expensive without insurance. The manufacturer lists the price of Tremfya at $14,566.44 per single subcutaneous injection or IV infusion. However, this is the list price, not necessarily the amount someone will pay at the pharmacy. The cash price can vary depending on the prescribed dose and dosage form, as well as the pharmacy where the prescription is filled.
Tremfya is available in several forms and strengths, including prefilled pens and syringes. Because dosing also varies depending on the condition being treated, the total cost of treatment can differ significantly from one patient to another.
The cost of Tremfya for those with insurance depends on the drug formulary, preference status, and copays. Without insurance, retail prices can differ depending on which pharmacy you use. No generic form exists, and one is not on the horizon either, based on Tremfya’s patents.
Compare Tremfya to related drugs |
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|---|---|---|---|
| Drug name | Price without insurance | SingleCare price | How to save |
| Tremfya (guselkumab) | $14,566.44 list price per dose | $12,431per 1, 1 mL of 100 mg/mL pen at Kroger or Harris Teeter | See updated prices |
| Bimzelx (bijukizumab) | $22,977 per 1, 2 mL of 320 mg/2 mL pen | $16,336 per 1, 2 mL of 320 mg/2 mL pen at Kroger or Harris Teeter | See updated prices |
| Humira (adalimumab) | $8,989 per 2, 1 auto-injector kits | $6,042 per 2, 1 auto-injector kits at Kroger or Harris Teeter | See updated prices |
| Adalimumab-aacf (generic Idacio) | $1,261 per 1 auto-injector kit | $881 per 1 auto-injector kit at Kroger or Harris Teeter | See updated prices |
| Enbrel (etanercept) | $9,808 per 4, 1 mL of 50 mg/mL syringes | $7,710 for 4, 1 mL of 50 mg/mL syringes at Kroger or Harris Teeter | See updated prices |
| Cimzia (certolizumab) | $7,549 per 1 prefilled syringe 2-pack | $6,163 per 1 prefilled syringe 2-pack at Kroger or Harris Teeter | See updated prices |
| Simponi (golimumab) | $8,193 per 1, 0.5 mL of 50 mg/0.5 mL pen | $6,519per 1, 0.5 mL of 50 mg/0.5 mL pen at Kroger or Harris Teeter | See updated prices |
| Skyrizi (risankizumab) | $14,916 per 1, 10 mL of 600 mg/10 mL vial | $10,360 per 1, 10 mL of 600 mg/10 mL vial at Kroger or Harris Teeter | See updated prices |
| Stelara (ustekinumab) | $35,340 per 1, 1 mL of 90 mg/mL syringe | $7,130 per 1, 1 mL of 90 mg/mL syringe at Kroger or Harris Teeter | See updated prices |
| Xeljanz (tofacitinib) | $7,594 per 60, 5 mg tablets | $4,457 per 60, 5 mg tablets at Kroger or Harris Teeter | See updated prices |
How to get Tremfya without insurance
The use of biologic medications has taken off, and their price can seem sky-high. Insurance may or may not cover the cost. To help patients navigate through insurance, pharmacy, and pricing aspects to get Tremfya, the drug’s manufacturer, Johnson & Johnson, has created the Tremfya with Me program. When it comes to savings, eligibility requirements for manufacturer patient assistance programs may need to be met. There are discount options that are more readily available.
1. Use a free SingleCare discount card
Free and easy to use, the SingleCare discount card can lower the price of Tremfya by just showing it to the pharmacist. Over 35,000 pharmacies in the U.S. accept SingleCare coupons. The discounted price will vary by establishment. Using singlecare.com or the SingleCare app to compare Tremfya prices at pharmacies near you can pay off.
2. Look into other biologics
From the table above, you can see that there is no shortage of options for biologic treatment of psoriasis, psoriatic arthritis, and ulcerative colitis. Generics are not available within the class because biologic drug development has been fairly recent, and manufacturing a generic for these complex molecules is expensive. Humira has been around long enough that biosimilars of it, like Idacio, are available.
The details of dosing will be important to consider when comparing options. Get the medical advice of your dermatologist, rheumatologist, or gastroenterologist about alternatives to Tremfya. Your healthcare provider can review differences in efficacy and side effects with you in order to factor these aspects, as well as price, into your decision-making.
3. Ask about alternatives to biologics
With biologics, considerable efficacy comes at a sizable cost. Other treatment options could be effective too, and at a fraction of the cost. For example, methotrexate can be effective for plaque psoriasis. It can cost as little as $231 for 72, 2.5 mg tablets, enough for three months of treatment when dosed as 15 mg once weekly. Discuss non-biologic treatment options with your doctor to determine if their lower efficacy or side effects make them unattractive alternatives despite their price.
The SingleCare prices in this article are the most accurate at the time of publishing in ZIP code 23666 as of Sep. 11, 2026. Prices vary by pharmacy. Visit our coupon page for updated drug prices at pharmacies near you.
- Tremfya drug patent profile, DrugPatentWatch (2024)
- Tremfya drug label, NIH DailyMed (2026)
- Humana Medicare drug pricing app, Humana (2024)
- Aetna Standard Control Plan formulary, Aetna (2024)
- Tremfya with Me program, Johnson & Johnson (2024)
- Tremfya cost support, Johnson & Johnson (2026)
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