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Key takeaways
Tremfya is a biologic medication, available by prescription, and administered as a subcutaneous injection every eight weeks for the treatment of psoriasis, psoriatic arthritis, and ulcerative colitis.
Insurance coverage for Tremfya varies between plans, with some not covering it at all and others requiring substantial copays.
Tremfya without insurance costs $17,873 per 100 mg dose.
Free SingleCare coupons can be used to save thousands of dollars on every Tremfya refill.
Less expensive biologic drugs and non-biologic alternatives may be viable options worth discussing with one’s healthcare team.
Tremfya (guselkumab) is a brand-name injectable medication that is prescribed to combat inflammation in the setting of severe plaque psoriasis, psoriatic arthritis, and ulcerative colitis. It is a biologic drug, more specifically a monoclonal antibody, that binds to the inflammatory mediator interleukin-23 (IL-23) to stop the autoimmune cascade fueling these health conditions. Like most biologic drugs, Tremfya carries a hefty price tag. Those hardest hit are people without health insurance. We will examine its expense and ways to save.
Related: Tremfya coupon | Tremfya details
Is Tremfya covered by insurance?
If you have insurance, the best way to know if you have coverage for Tremfya is to check your insurance provider’s formulary. Insurance coverage will vary from plan to plan. For example, Humana Medicare’s formulary lists Tremfya as not covered, while Aetna’s Standard Plan labels the drug as a preferred specialty product. Preferred status often means a lower copay for meds that are covered compared to non-preferred options. These details will determine how much you have to pay out-of-pocket for Tremfya.
How much does Tremfya cost without insurance?
The cost of Tremfya for those with insurance depends on the drug formulary, preference status, and copays. Without insurance, retail prices can differ depending on which pharmacy you use. No generic form exists, and one is not on the horizon either based on Tremfya’s patents.
The retail price of Tremfya is $17,873 for a single-dose 100 mg pen injector. Tremfya is usually given as a 100 mg injection every 8 weeks, except for the first two doses, which are only separated by 4 weeks. That adds up to $168,000 in the first year of treatment and $144,000 annually for each subsequent year.
Tremfya’s expense rightfully sends people in search price comparisons. The drug does not stand alone as an option for treatment of psoriasis, psoriatic arthritis, or ulcerative colitis. Although price is only one factor to consider, it remains one of practical importance.
Compare Tremfya to related to drugs |
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|---|---|---|---|
| Drug name | Price without insurance of brand-name drug | SingleCare price | Savings options |
| Tremfya (guselkumab) | $17,873 per 1, 1 mL of 100 mg/mL pen | $12,168 per 1, 1 mL of 100 mg/mL pen of brand-name Tremfya | See updated prices |
| Bimzelx (bijukizumab) | $21,892 per 1, 2 mL of 320 mg/2 mL pen | $15,499 per 1, 2 mL of 320 mg/2 mL pen of brand-name Bimzelx | See updated prices |
| Humira (adalimumab) | $8,900 per 2, 1 auto-injector kits | $6,015 per 2, 1 auto-injector kits of brand-name Humira | See updated prices |
| Adalimumab-aacf (generic Idacio) | $1,261 per 1 auto-injector kit of generic Idacio | $881 per 1 auto-injector kit of generic Idacio | See updated prices |
| Enbrel (etanercept) | $9,518 per 4, 1 mL of 50 mg/mL syringes | $7,312 for 4, 1 mL of 50 mg/mL syringes of brand-name Enbrel | See updated prices |
| Cimzia (certolizumab) | $7,549 per 1 prefilled syringe 2-pack | $5,837 per 1 prefilled syringe 2-pack of brand-name Cimzia | See updated prices |
| Simponi (golimumab) | $7,887 per 1, 0.5 mL of 50 mg/0.5 mL pen | $6,193 per 1, 0.5 mL of 50 mg/0.5 mL pen of brand-name Simponi | See updated prices |
| Skyrizi (risankizumab) | $13,305 per 1, 10 mL of 600 mg/10 mL vial | $9,834 per 1, 10 mL of 600 mg/10 mL vial of brand-name Skyrizi | See updated prices |
| Stelara (ustekinumab) | $17,022 per 1, 0.5 mL of 45 mg/0.5 mL syringe | $3,566 per 1, 0.5 mL of 45 mg/0.5 mL syringe of generic Stelara | See updated prices |
| Xeljanz (tofacitinib) | $7,493 per 60, 5 mg tablets | $5,455 per 60, 5 mg tablets of brand-name Xeljanz | See updated prices |
Prescription drug prices often change. These are the most accurate medication prices at the time of publishing in ZIP code 23666 as of Dec. 30, 2025. The listed price without insurance references the price of brand-name drugs (unless otherwise specified). The listed SingleCare price references the price of generic drugs if available.
How to get Tremfya without insurance
The use of biologic medications has taken off, and their price can seem sky-high. Insurance may or may not cover the cost. To help patients navigate through insurance, pharmacy, and pricing aspects to get Tremfya, the drug’s manufacturer Johnson and Johnson has created the Tremfya with Me program. When it comes to savings, eligibility requirements for manufacturer patient assistance programs may need to be met. There are discount options that are more readily available.
1. Get a SingleCare discount card
Free and easy to use, the SingleCare discount card can lower the price of Tremfya by just showing it to the pharmacist. The price of a 100 mg pen of the medication can drop from $17,873 to $12,168. Taken every eight weeks, SingleCare users save $5,705 per dose and more than $37,000 per year.
2. Shop around at different pharmacies
Over 35,000 pharmacies in the United States take SingleCare coupons. The discount price will differ between establishments. The cost of Tremfya varies sometimes by $1,000+, depending on the pharmacy you use. Using singlecare.com or the SingleCare app to compare Tremfya prices at pharmacies near you always pays off.
3. Look into other biologics
From the table above, you can see that there is no shortage of options for biologic treatment of psoriasis, psoriatic arthritis, and ulcerative colitis. Generics are not available within the class because biologic drug development has been fairly recent, and manufacturing a generic for these complex molecules is expensive. Humira has been around long enough that biosimilars of it, like Idacio, are available.
The biosimilars represent some of the least expensive options. With a SingleCare discount, generic Idacio costs $881 for a one-month supply. A patient could spend $1,762 for two months of generic Idacio therapy or pay $12,168 for a two-month supply of Tremfya.
The details of dosing will be important to consider when comparing options. Get the medical advice of your dermatologist, rheumatologist, or gastroenterologist about alternatives to Tremfya. Your healthcare provider can review differences in efficacy and side effects with you in order to factor these aspects, as well as price, into your decision-making.
4. Ask about alternatives to biologics
With biologics, considerable efficacy comes at a sizable cost. Other treatment options could be effective too, and at a fraction of the cost. For example, methotrexate can be effective for plaque psoriasis. It can cost as little as $231 for 72, 2.5 mg tablets, enough for three months of treatment when dosed as 15 mg once weekly. Discuss non-biologic treatment options with your doctor to determine if their lower efficacy or side effects make them unattractive alternatives despite their price.
The SingleCare prices in this article are the most accurate at the time of publishing in ZIP code 23666 as of Dec. 30, 2025. Prices vary by pharmacy. Visit our coupon pages for updated drug prices near you.
- Tremfya drug patent profile, DrugPatentWatch (2024)
- Tremfya drug label, NIH DailyMed (2024)
- Humana Medicare drug pricing app, Humana (2024)
- Aetna Standard Control Plan formulary, Aetna (2024)
- Tremfya with Me program, Johnson and Johnson, Inc (2024)