What is Atenolol: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Atenolol is a generic prescription drug used for high blood pressure and heart problems. It belongs to a family of medications called cardioselective beta blockers. These drugs widen blood vessels and decrease the amount of work demanded by the heart. Atenolol is only taken as tablets; doses are usually taken once daily.

Atenolol overview

BRAND NAMES:

  • Tenormin

Generic Names:

  • Atenolol

Uses:

  • Treats high blood pressure and chest pain. It also reduces the risk of complications and death after a heart attack.

Therapeutic Classes:

  • Beta blocker, cardioselective beta blocker, antihypertensive, antianginal, antiarrhythmic, cardiovascular agent

Forms:

  • Tablet

How it’s taken:

  • By mouth

What is Atenolol used for?

Atenolol is used for a variety of cardiovascular problems, including high blood pressure (hypertension), chest pain (angina), and heart attack. For heart attacks, doctors use atenolol to prevent further heart attacks and reduce the chances of dying. In addition to these treatments approved by the U.S. Food and Drug Administration, healthcare professionals may use atenolol off-label for other reasons such as migraine prevention, rapid heart rate (tachycardia), and tremor.

What form(s) does Atenolol come in

  • Tablet

    • 25 mg

    • 50 mg

    • 100 mg

What are common Atenolol doses?

  • For high blood pressure: 50–100 mg tablet taken once per day

  • For chest pain (angina): 50–200 mg taken orally once per day

  • For heart attack (acute myocardial infarction): 50 mg tablet twice daily or 100 mg taken orally once per day for six to nine days or until hospital discharge

Find more information about atenolol dosage, forms, and strengths here.

Common Atenolol prescriptions

  • Atenolol
    30 tablets bottle

  • Atenolol
    30 tablets disp pack

  • Atenolol
    100mg tablet

  • Atenolol
    25mg tablet

  • Atenolol
    50mg tablet

How to take Atenolol

  • Take atenolol tablets as directed. The dose may need to be changed depending on side effects.

  • Atenolol can be taken with or without food, but it is more effective when taken on an empty stomach.

  • Try to take atenolol doses at the same time(s) every day.

  • Swallow atenolol tablets with a glass of water.

  • Store the medicine in a light-resistant, closed container at room temperature.

What to do if you miss a dose of Atenolol

  • Do not miss doses of atenolol. Missing a dose may cause problems.

  • Ask the prescribing healthcare provider what to do if a dose is missed.

  • The doctor will probably advise you to take the missed dose unless it’s almost time for the next dose. In that case, ignore the missed dose and take the next dose at its regular time.

  • Never take extra atenolol tablets to make up for a missed dose.

Atenolol contraindications

  • This medicine is not right for everyone. 

  • Do not take atenolol tablets if you have had an allergic reaction to atenolol or any other beta blocker.

  • Atenolol can also not be taken by people with severe heart rhythm problems. Since these conditions are very serious, and some are immediately life-threatening, a doctor will know that you have them. 

  • Atenolol cannot be safely given to people with untreated adrenal gland cancer.

Atenolol warnings

  • Tell any doctor or other healthcare provider who treats you that you are using atenolol. Healthcare professionals may tell you to stop using this medicine several days before major surgery or certain medical tests.

  • You will need regular doctor’s visits and lab tests so the doctor can monitor treatment effectiveness and medication side effects. Keep all appointments.

  • Tell the doctor if you are pregnant or breastfeeding. Atenolol may harm an unborn fetus.

  • Tell the doctor if you have:

    • Heart failure

    • Any previous heart attack

    • Airway constriction problems such as asthma, bronchitis, or emphysema

    • Kidney disease

    • Diabetes or low blood sugar

    • Overactive thyroid

    • Adrenal gland cancer 

  • This medicine may worsen the symptoms of heart failure or cause low blood pressure.

  • Atenolol may mask the symptoms of low blood sugar (hypoglycemia), raising the risk of severe hypoglycemia. Tell the doctor if you are diabetic, fasting, or not eating.

  • This medicine may make you dizzy or drowsy. Do not drive or do anything else that requires alertness until you know how this medicine affects you.

  • Atenolol should never be stopped until consulting with a doctor. Doing so may result in chest pain or heart attack. The doctor may need to reduce the dose gradually when it’s time to stop.

Atenolol interactions

  • Atenolol can cause problems when combined with other drugs, so tell the prescribing healthcare provider about all prescription drugs, over-the-counter medications, and supplements you use, particularly:

    • Other beta blockers

    • Calcium channel blockers

    • Heart rhythm medications, including amiodarone and disopyramide

    • Heart treatments called digitalis glycosides, such as digoxin

    • Drugs that reduce a neurotransmitter in the heart (catecholamine-depleting drugs), such as amphetamines

    • The blood pressure drugs reserpine or clonidine

    • The pain reliever indomethacin

  • Atenolol cannot be safely combined with general anesthetics. It may be necessary to interrupt atenolol treatment before major surgery.

  • Tell other healthcare providers you are using this medicine before they prescribe new medications.

Atenolol side effects

Serious side effects

Talk to a doctor if you notice any signs or symptoms of a possible serious side effect, including:

  • Chest pain that may spread to your arms, jaw, back, or neck, trouble breathing, nausea, unusual sweating

  • Slow, fast, or irregular heartbeat

  • Worsening chest pain or new chest pain

  • Rapid weight gain, swelling in your hands, ankles, or feet, trouble breathing

  • Lightheadedness, dizziness, fainting

  • Difficulty breathing, shortness of breath, asthma-like symptoms

  • Sudden shortness of breath, chest pain, dizziness, fainting, coughing, coughing up blood

  • Changes in urination, swelling of the legs, ankles, and feet, itchy skin, confusion

  • Vision changes

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

Less serious side effects

  • Dizziness

  • Tiredness

  • Dizziness

  • Cold hands and feet

  • Depression

  • Fatigue

Find more detailed information about atenolol's side effects here.

Sources:

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