Duloxetine is a generic prescription drug used to treat major depressive disorder, anxiety, fibromyalgia, diabetic neuropathy, and chronic musculoskeletal pain. The average retail price of Duloxetine delayed-release capsules is $228.79 for 30, 60mg capsules delayed release particles. By using a free SingleCare Duloxetine coupon, you can save on your prescription and get the price as low as $8.17 for 30, 60mg capsules delayed release particles at participating pharmacies.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 12/05/2025
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Duloxetine is a generic prescription drug used to treat major depressive disorder, anxiety, fibromyalgia, diabetic neuropathy, and chronic musculoskeletal pain. The average retail price of Duloxetine delayed-release capsules is $228.79 for 30, 60mg capsules delayed release particles. By using a free SingleCare Duloxetine coupon, you can save on your prescription and get the price as low as $8.17 for 30, 60mg capsules delayed release particles at participating pharmacies.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Duloxetine Hcl Retail Price | Duloxetine Hcl SingleCare Price |
|---|---|---|
| CVS Pharmacy | $212.30 | $39.76 |
| Walmart | $30.00 | $16.20 |
| Walgreens | $213.68 | $74.01 |
| Kroger Pharmacy | $215.20 | $10.52 |
| Albertsons Pharmacy | $197.73 | $23.63 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Duloxetine is a generic prescription drug used to treat major depressive disorder, anxiety, fibromyalgia, diabetic neuropathy, and chronic musculoskeletal pain. The average retail price of Duloxetine delayed-release capsules is $228.79 for 30, 60mg capsules delayed release particles. By using a free SingleCare Duloxetine coupon, you can save on your prescription and get the price as low as $8.17 for 30, 60mg capsules delayed release particles at participating pharmacies.
The generic of Duloxetine costs $8.17 for 30, 60mg capsules delayed release particles with a free Duloxetine coupon from SingleCare. You could pay less depending on your prescription details. Use the dropdown menu above to update your prescription details (i.e., brand/generic, quantity, form, dosage) to get the most accurate prices of Duloxetine with SingleCare at your local pharmacies.
Without insurance, the average cost of a 30-day supply of Duloxetine is $228.79 for 30, 60mg capsules delayed release particles. Fortunately, you can use a SingleCare savings card to lower the price to $8.17 for 30, 60mg capsules delayed release particles. By joining SingleCare’s loyalty program, you can earn bonus savings on Duloxetine refills or other prescription medications.
Nearly all health insurance plans cover Duloxetine, but insured patients still have to pay a copay or other fees. The out-of-pocket cost of Duloxetine with insurance depends on the insurance plan, dosage, and quantity prescribed. Ask the insurance provider or pharmacist for specific information on your out-of-pocket costs. Then compare this out-of-pocket cost with the SingleCare discounted Duloxetine price. It may be more cost-effective to use SingleCare drug coupons instead of your insurance.
Medicare Part D and Medicare Advantage plans usually cover Duloxetine, but there may be restrictions because it’s considered a higher-risk drug in seniors. The out-of-pocket costs will depend on your specific plan and your current coverage status. If your Medicare insurance coverage doesn’t fully reduce your cost, you can use a SingleCare coupon, which may lower your cost to $8.17 for 30, 60mg capsules delayed release particles.
Most Medicaid plans cover Duloxetine for FDA-approved conditions; however, coverage and out-of-pocket costs will vary depending on the state. Medicaid patients without Duloxetine coverage can use a SingleCare discount card at a participating pharmacy. The lowest SingleCare Duloxetine price is $8.17 for 30, 60mg capsules delayed release particles.
Cymbalta and Drizalma Sprinkle are the brand-name versions of Duloxetine. Unlike the generic version, both are premium-priced. SingleCare’s prescription drug discount program can reduce the cost of these and other brand-name medications by up to 80%.
Duloxetine is higher in price than many other commonly-prescribed generic drugs. The options for saving money on generic drugs are relatively limited. Generic manufacturers do not typically offer manufacturer coupons, patient assistance programs, or rebates.
Patients who are paying cash for their Duloxetine prescription or facing a high copay cost can reliably save money by using SingleCare’s prescription savings program. A free coupon from SingleCare can reduce the price of Duloxetine to as low as $8.17 for 30, 60mg capsules delayed release particles.
People can also save money by enrolling in the Medicare Low-Income Subsidy (for individuals with Medicare coverage), Medicaid, or a subsidized prescription drug program at a local 340B clinic or hospital. People who can’t meet the income requirements can shop online and local pharmacies for the lowest Duloxetine price.
Prescription drugs similar to Duloxetine called SNRIs (serotonin and norepinephrine reuptake inhibitors) cost about the same or more than duloxetine. The lowest-cost SNRI is venlafaxine. It works much the same way and has similar side effects and drug interactions.
For lower-cost treatment options, ask a healthcare professional for medical advice about other drug classes FDA-approved to treat depression or anxiety. The least expensive are tricyclic antidepressants, such as amitriptyline. They are generally the least expensive generic drugs available in a pharmacy. An SSRI (selective serotonin reuptake inhibitor), like fluoxetine, may be a more appropriate treatment option. The most commonly-prescribed SSRIs are only a fraction of the cost of Duloxetine.
For other health conditions, such as other mental health conditions, fibromyalgia, or diabetic neuropathy, ask the prescriber for medical advice.
You can use SingleCare coupons at most national pharmacies and grocers, i.e., Walgreens, Kroger, Walmart, CVS, Safeway, and more. Text, email, print, or save your free Duloxetine coupon to your digital wallet and show your pharmacist at the counter.
Gerardo Sison, Pharm.D., graduated from the University of Florida. He has worked in both community and hospital settings, providing drug information and medication therapy management services. As a medical writer, he hopes to educate and empower patients to better manage their health and navigate their treatment plans.
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved