Minivelle is a brand-name prescription medication used to treat certain symptoms of menopause such as hot flashes, vaginal dryness, irritation, and burning. It is also used to prevent postmenopausal osteoporosis (a condition where the bones become fragile), and to treat disorders of the ovaries. A generic version of Minivelle has been approved by the FDA but it may not be commercially available yet. Minivelle costs around $285.37 per 1, 1 box (8 twice weekly patches), 0.05mg/24 hr box but you could save on Minivelle with SingleCare and pay just $43.88. Use our SingleCare Minivelle coupon to save up to 80% on your next prescription refill.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 12/05/2025
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Minivelle is a brand-name prescription medication used to treat certain symptoms of menopause such as hot flashes, vaginal dryness, irritation, and burning. It is also used to prevent postmenopausal osteoporosis (a condition where the bones become fragile), and to treat disorders of the ovaries. A generic version of Minivelle has been approved by the FDA but it may not be commercially available yet. Minivelle costs around $285.37 per 1, 1 box (8 twice weekly patches), 0.05mg/24 hr box but you could save on Minivelle with SingleCare and pay just $43.88. Use our SingleCare Minivelle coupon to save up to 80% on your next prescription refill.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Minivelle Retail Price | Estradiol Retail Price | Estradiol SingleCare Price |
|---|---|---|---|
| CVS Pharmacy | $124.00 | $108.48 | $72.72 |
| Walmart | - | $58.47 | $52.70 |
| Walgreens | $292.00 | $52.38 | $45.86 |
| Kroger Pharmacy | $116.00 | $112.20 | $73.04 |
| Albertsons Pharmacy | - | $136.12 | $58.56 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Minivelle is a brand-name prescription medication used to treat certain symptoms of menopause such as hot flashes, vaginal dryness, irritation, and burning. It is also used to prevent postmenopausal osteoporosis (a condition where the bones become fragile), and to treat disorders of the ovaries. A generic version of Minivelle has been approved by the FDA but it may not be commercially available yet. Minivelle costs around $285.37 per 1, 1 box (8 twice weekly patches), 0.05mg/24 hr box but you could save on Minivelle with SingleCare and pay just $43.88. Use our SingleCare Minivelle coupon to save up to 80% on your next prescription refill.
If you are not covered by a health insurance plan, you may be spending as much as $285.37 on your Minivelle prescription. SingleCare can help you to reduce this total. Just use our SingleCare Minivelle coupon and pay as low as $43.88 for your next refill.
Minivelle copays usually vary based on the type of insurance plan that you currently have. You may need to contact your insurance provider or local pharmacy to find out how much Minivelle costs under your healthcare coverage.
With SingleCare's Minivelle discount card, you can pay as little as $43.88, which may even be cheaper than your insurance. Compare pricing today to find out how much you can save.
Minivelle is currently not covered by Medicare. This generally means that you will end up paying full price for your medication. However, with a free SingleCare savings card you can save on your prescription by paying just $43.88 at participating pharmacies such as CVS, Walmart, Kroger, Fry's, Harris Teeter, and Walgreens.
A generic version of Minivelle has been approved by the FDA, but it may not yet be commercially available.
Minivelle is an FDA-approved prescription drug used by women to treat symptoms of menopause, such as hot flashes and vaginal dryness. These symptoms usually occur due to the body producing less estrogen in women as they age. This medication may also be used by women who are naturally unable to produce enough estrogen due to certain medical conditions, such as hypogonadism or ovarian failure.
The active ingredient in Minivelle is estradiol which is a form of estrogen. Minivelle helps to treat the symptoms listed above by increasing estrogen levels. This medication may also be used by women after menopause to prevent bone loss caused by osteoporosis.
Minivelle comes in the form of a transdermal patch that is applied to the skin. It is often applied to the skin twice weekly. However, the exact dosage for this medication will be advised by your healthcare provider after taking your medical history into consideration. These patches should be applied to a different area of skin every time they are used to ensure maximum effectiveness. It is recommended to apply Minivelle to a clean, dry area around the lower abdomen. It should never be applied to the breasts.
Common side effects associated with using Minivelle include irritation and skin redness at the site of application on your skin, nausea, vomiting, bloating, headaches, breast tenderness, and weight changes. In addition, Minivelle may cause back pain, indigestion, or intermenstrual bleeding. Other side effects may also occur since this is not a complete list.
Allergic reactions to Minivelle are very rare but require immediate medical attention. Consult medical care if you experience a severe rash, trouble bleeding, or severe swelling around the site of application.
Tell your doctor immediately if you experience any serious side effects such as breast lumps or unusual vaginal bleeding. In rare cases, serious problems stemming from blood clots may occur, such as heart attacks, strokes, and deep vein thrombosis. Ask your healthcare specialist for medical advice if you have a family history of heart disease. Tell your doctor if you have a history of thyroid problems, breast cancer, liver impairment, or blood clotting disorders before using Minivelle.
Gerardo Sison, Pharm.D., graduated from the University of Florida. He has worked in both community and hospital settings, providing drug information and medication therapy management services. As a medical writer, he hopes to educate and empower patients to better manage their health and navigate their treatment plans.
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved