How much does Restasis cost with Medicare?

In this article:

• Does Medicare cover Restasis?
• How much does Restasis cost without insurance?
• How much does Restasis cost with Medicare?
• Restasis assistance for Medicare patients
• Does Medicare cover Restasis?

In this article

• Does Medicare cover Restasis?
• How much does Restasis cost without insurance?
• How much does Restasis cost with Medicare?
• Restasis assistance for Medicare patients
• Does Medicare cover Restasis?

Restasis is the brand name for cyclosporine, a prescription eye drop medication used to increase tear production in people with dry eye disease. It works by suppressing the immune response, which decreases eye inflammation and allows for natural tear production. Restasis is FDA approved for use in adults and children 16 years and older with chronic dry eye.

Read on for how to save on Restasis if you have Medicare, including Restasis patient assistance for Medicare, Restasis alternatives, and more.

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$123.70

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Does Medicare cover Restasis?

Prescription drugs for people on Medicare are covered by Medicare Part D. Many, but not all, Medicare Part D plans cover Restasis, but beneficiaries may be responsible for copays or coinsurance, which vary by plan. They may also require prior authorization or step therapy, which involves trying a less expensive medication first.

Mara Woloshin, APR, fellow PRSA, and Medicare and Medicaid consultant, says you can file an appeal if your health insurance company denies your prescription coverage. “I strongly recommend that all patients file an Appeal through their health plan,” Woloshin says. Every health insurance plan must carry appeal forms on its website, and all health insurance appeals must be responded to within 72 hours, Woloshin notes.

“Patients need to be persistent,” she says. “Most first-time appeals are denied. Typically, second (and even third appeals) are approved.”

How much does Restasis cost without insurance?

Without insurance, Restasis costs an average of $411 for 30 single-use vials, a 15-day supply. A 30-day supply would cost about $822. 

One bottle of Restasis Multidose, which contains 30 days of doses, costs an average of $831.  

The generic version of Restasis, cyclosporine, is available in single-use vials. Unfortunately, generic cyclosporine costs almost as much as Restasis. 

How much does Restasis cost with Medicare?

The cost of Restasis with Medicare Part D depends on the details of the plan. Check your Part D formulary to see whether it covers Restasis and how much of a copay or coinsurance you’ll be responsible for.

Restasis assistance for Medicare patients

If your Medicare Part D plan doesn’t cover Restasis, one option is to see if you can get a prescription for the generic version of Restasis, which is cyclosporine, sold as a cyclosporine ophthalmic emulsion. The FDA notes that generic versions of prescription medications work just as well as brand versions. 

Still, if your Medicare Part D plan doesn’t cover Restasis, there are other ways you can save. Here are some options.

SingleCare coupons

Using your SingleCare prescription discount card can save you money on your Restasis prescription. Simply present your free card or coupon to pharmacy staff when picking up your prescription to see how much you can save.

Prescription drug prices often change. These are the most accurate medication prices at the time of publishing in ZIP code 23666 as of Jan. 7, 2026. The listed price without insurance references the price of brand-name drugs (unless otherwise specified). The listed SingleCare price references the price of generic drugs if available.

Medicare Extra Help

For low-income individuals on Medicare, the Medicare Extra Help program is a program to consider. To qualify, you must meet the income limits for the year and have limited assets.

Medicare Extra Help “virtually eliminates the costs for prescription drugs,” Woloshin says. Additionally, if you meet the Medicare Extra Help requirement, you may also be eligible for Limited Income Subsidy (LIS) from Medicare, “which dramatically reduces medical costs, many down to $0,” Woloshin shares.

Restasis patient assistance programs

Sometimes Restasis coupons are available through the manufacturer. For example, the Restasis Savings Program can help patients with commercial prescription insurance coverage, but patients enrolled in Medicare, Medicaid, or any other federal, state, or government-funded healthcare program are ineligible. However, another program called myAbbVie Assist may help.

Additionally, as Woloshin shares, people on Medicare can apply for support from their state pharmacy association. You can search for your state pharmacy association on the Medicare website here. Finally, Woloshin says many health clinical systems offer patient grants and support.

Free samples at healthcare providers’ offices

If you are waiting for your health insurance plan to approve your Restasis prescription, you can ask your healthcare provider if they have a free sample you can use while you wait. Bear in mind, though, that this isn’t a sustainable plan, since Restasis is a medication meant to be used on an ongoing basis. 

Restasis alternatives

Restasis isn’t the only way to treat dry eye syndrome. Certain medications similar to Restasis may be more affordable to you. Restasis alternatives include:

• Cequa
• Vevye
• Xiidra
• Tyrvaya
• Miebo

At the same time, not all of these medications are cheaper than Restasis without insurance, and not all of them are more likely to be covered by Medicare than Restasis. It’s best to discuss any alternative medications with your healthcare provider or pharmacist. You can also ask their advice about navigating health insurance coverage and saving on Restasis.