What is Rozlytrek? Uses, warnings & side effects

How to take Rozlytrek

• Your doctor will tell you how much medicine to use. Do not use more than directed.

• Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

• Swallow the capsule whole. Do not open, crush, chew, or dissolve it.

• Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose. Take a dose as soon as you remember. If your next dose is within 12 hours, skip the missed dose and return to your regular dosing schedule. If you vomit after taking a dose, take a dose as soon as possible.

• Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

What to do if you miss a dose of Rozlytrek

Rozlytrek contraindications - Who shouldn't take Rozlytrek?

• This medicine is not right for everyone. Do not use it if you had an allergic reaction to entrectinib, or you are pregnant.

Rozlytrek warnings

• Oral routeIt is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant. If you are female and able to get pregnant, your doctor may give you a pregnancy test before you start using this medicine to make sure you are not pregnant. Use an effective form of birth control during treatment and for at least 5 weeks after the last dose. Male patients who have female partners should use effective birth control during treatment and for at least 3 months after the last dose.

• Do not breastfeed during treatment and for 7 days after your last dose of this medicine.

• Tell your doctor if you have kidney disease, liver disease, eye or vision problems, heart disease, or nervous system problems.

• This medicine may cause the following problems:Congestive heart failureNervous system problemsIncreased risk of bone fracturesLiver problemsHigh uric acid in the bloodHeart rhythm problems, including QT prolongationEye or vision problems

• This medicine may cause dizziness, tiredness, or vision problems. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

• Oral routeMedicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

• Oral routeCancer medicine can cause nausea or vomiting, sometimes even after you receive medicine to prevent these effects. Ask your doctor or nurse about other ways to control any nausea or vomiting that might happen.

• Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

• Keep all medicine out of the reach of children. Never share your medicine with anyone.

Rozlytrek interactions & what to avoid when taking Rozlytrek

• Some medicines can affect how entrectinib works. Tell your doctor if you are using digoxin, itraconazole, lansoprazole, midazolam, or rifampin.

• Do not eat grapefruit or drink grapefruit juice while you are using this medicine.