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Key takeaways
Linzess (linaclotide) is an FDA-approved prescription medication for IBS-C, CIC, and functional constipation. It has a high retail cost of around $736 for a 30-day supply without discounts, and there are currently no generic versions available.
Most commercial insurance plans, Medicaid, and Medicare Part D cover Linzess, but copay amounts vary.
Patients can reduce Linzess costs through SingleCare discount coupons, the Linzess Savings Card, and other savings options.
Linzess (linaclotide) is a prescription medication approved by the Food and Drug Administration (FDA) to treat irritable bowel syndrome with constipation (IBS-C), chronic idiopathic constipation (CIC), and functional constipation. It’s an effective medication, but it can be expensive without insurance or a Linzess coupon. Keep reading to learn about the Linzess copay card, coupons, and other ways to save on your prescription.
How much does Linzess cost?
The average retail price for Linzess is $736 for 30, 145 microgram (mcg) capsules if you pay out of pocket without discounts. Currently, there aren’t any generic versions of Linzess available, so people who are uninsured can expect to pay the full retail price for the medication.
Save up to 80% on Linzess with SingleCare
Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.
How to save money on Linzess
If you’re uninsured or your insurance doesn’t provide enough coverage, here’s how to get Linzess cheaper.
1. Free Linzess coupons
You can lower the costs of Linzess with a SingleCare prescription discount card or coupon. “SingleCare offers coupons that can bring down the price of prescriptions, sometimes even lower than your insurance copay,” says Sean Ormond, MD, a dual board-certified physician in anesthesiology and interventional pain management and owner of Atlas Pain Specialists of Phoenix, Arizona.
SingleCare is free and easy to use. Simply search for your medication on the SingleCare website or app, and compare prices at pharmacies near you. Choose the Linzess coupon from the pharmacy offering the lowest price, and present it at checkout to pay the advertised price. With a SingleCare Linzess coupon, you can pay $252 instead of $736 for 30, 145 mcg capsules.
What’s great about the SingleCare discount card is that you can use it whether or not you have insurance. You’ll pay a discounted price for Linzess, but it’ll be much cheaper than paying out of pocket without any discounts.
2. Linzess Savings Card
The manufacturers of Linzess offer a Linzess savings card that allows eligible patients to pay as little as $30 for a 30- or 90-day prescription. There are specific requirements that need to be met, though, and patients enrolled in Medicare, Medicaid, or other federal or state programs (e.g., TRICARE, VA, or state assistance programs) are ineligible.
3. Patient assistance
The myAbbVie Assist Program is available for people who are uninsured, are receiving Medicare, or have commercial insurance that doesn’t provide enough coverage for the medication. You can complete an online or paper application to determine your eligibility for this program.
4. Non-profit organizations
“Organizations like NeedyMeds or the Patient Advocate Foundation are great resources,” Dr. Ormond says. “They help connect people to financial assistance programs that can reduce or cover the cost of medications.”
NeedyMeds offers patient assistance programs, coupons, rebates, savings cards, free trial offers, free samples, and other services to make healthcare more affordable for people in need.
One of the programs offered at the Patient Advocate Foundation is the Co-Pay Relief Program. This program provides financial aid to insured patients who meet the eligibility requirements to help them pay for the prescriptions and/or treatments they need. You must have insurance and meet residential and income criteria to be accepted into the program.
You can reach out to these programs to get additional information on enrollment and other available resources to lower the costs of Linzess.
5. Medicare Extra Help
If you have a Medicare Part D plan, you may want to consider applying for the Extra Help program. This program is designed to help people with financial strain and limited resources pay their premiums, deductibles, coinsurance, and other costs. You can apply for Extra Help if you have full Medicaid coverage, receive help from your state to pay your Part B premiums, and/or have Supplemental Security Income (SSI) payments from Social Security. If you’re accepted into the program, you’ll pay up to $12.65 for brand-name drugs like Linzess in 2026.
Does insurance cover Linzess?
According to the drug manufacturers AbbVie and Ironwood Pharmaceuticals, 98% of commercial health insurance plans cover Linzess prescriptions.
For Medicare or private health insurance plans, you can check whether Linzess or other medications are covered by looking at their formularies. A formulary is a list of prescription drugs covered by your health insurance or prescription drug plan.
For example, some Medicare plans consider Linzess a Tier 3 approved drug with a maximum of one capsule per day. Tier 3 drugs are higher-cost, primarily brand-name drugs that are non-preferred by insurers. You can expect higher copays for medications in this tier than for generic and preferred prescription medications at the lower tiers.
Medicaid may also cover Linzess, but it may vary by state. According to the 2025 Medicaid Drug Formulary for the Neighborhood Health Plan of Rhode Island, Linzess is considered a Tier 2 drug, which is categorized similarly to Tier 3 Medicare drugs.
However, your insurance company may recommend trying a cheaper alternative before covering Linzess. This is called step therapy.
Is there a cheaper alternative to Linzess?
Fortunately, if you’re uninsured or your insurance doesn’t cover the costs of Linzess, your healthcare provider may recommend an FDA-approved Linzess alternative at a lower price.
Linzess alternatives and costs |
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|---|---|---|---|
| Drug name | Uses | SingleCare price | Savings options |
| Amitiza (lubiprostone) | IBS-C in women ages 18 years and older, CIC in adults, and opioid-induced constipation (OICD) in adults with chronic pain | $38 for 60, 24 mcg capsules of generic Amitiza at CVS | See latest prices |
| Lactulose (oral solution) | Chronic constipation | $9 for 1, 473 mL bottle of generic lactulose at Kroger | See latest prices |
| Motegrity (prucalopride) | CIC | $43 for 30, 2 mg tablets of generic Motegrity at Publix | See latest prices |
| Trulance (plecanatide) | IBS-C, CIC | $553 for 30, 3 mg tablets of brand-name Trulance at Kroger | See latest prices |
| Ibsrela (tenapanor) | IBS-C | $2,001 for 60, 50 mg tablets of brand-name Ibsrela at Kroger | See latest prices |
Prescription drug prices often change. These are the most accurate medication prices at the time of publishing in ZIP code 23666 as of Jan. 27, 2026. The listed SingleCare price references the price of generic drugs if available.
Your healthcare provider can help you decide which alternative medication is best for treating your symptoms.
- Insurance coverage for Linzess, AbbVie and Ironwood Pharmaceuticals, Inc.
- How do drug plans work, Centers for Medicare & Medicaid Services
- 2025 Medicaid Drug Formulary, Neighborhood Health Plan of Rhode Island (2025)
- MyAbbVie Assist, AbbVie
- NeedyMeds, NeedyMeds
- Home, Patient Advocate Foundation
- Patients & Family – Co-Pay Relief, Patient Advocate Foundation
- Help with drug costs, Centers for Medicare & Medicaid Services