How to save on Trintellix: Savings card & more

In this article:

• Trintellix cost
• Trintellix vs. SSRI cost
• How to save
• Alternatives
• FAQs

In this article

• Trintellix cost
• Trintellix vs. SSRI cost
• How to save
• Alternatives
• FAQs

Trintellix (vortioxetine) is a serotonin modulator and stimulator (SMS), which is an atypical antidepressant that shifts serotonin levels in the brain to treat adults with major depressive disorder (MDD). Currently, there is no generic version of Trintellix. We’ll outline ways to save on Trintellix, including free SingleCare coupons, a Trintellix savings card, and the Trintellix patient assistance program.

How much does Trintellix cost?

Without insurance, the average retail price of Trintellix is about $689 for 30, 20 mg tablets. The cost varies depending on your pharmacy, prescribed dosage and frequency, insurance, and other factors.

Many commercial health insurance plans cover Trintellix, and some Medicaid, Medicare, and VA insurance plans may cover it. Check your insurance company’s formulary list or contact an insurance agent to see if it’s covered under your plan. It’s also a good idea to ask about prior authorization—some insurance providers might require it for Trintellix. 

Why does Trintellix cost more than typical SSRIs?

Trintellix is considered to be an atypical antidepressant. It usually costs more than typical depression medications, such as selective serotonin reuptake inhibitors (SSRIs), because it does not have a generic version available yet. However, its patent is due to expire in June 2026, which would allow other manufacturers to make vortioxetine, the generic version of Trintellix. Until then, there are a few options to save on the cost of Trintellix.

How to save money on Trintellix

Trintellix coupons, the Trintellix savings card, and the manufacturer’s patient assistance program are three ways to save on your Trintellix prescription. 

1. SingleCare Trintellix coupons

SingleCare negotiates with retail pharmacies to help make medication more affordable to patients. 

• Best for: Patients who are uninsured or underinsured can benefit from SingleCare coupons, although insured patients can use SingleCare coupons as well—just not in conjunction with prescription drug coverage through their insurance.
• Savings: A free SingleCare Trintellix coupon could save you up to $192 on a month’s supply of Trintellix, costing you around $491 for 30, 20 mg tablets that average around $684 at retail. SingleCare prices vary by form, strength, quantity, and pharmacy. 
• Eligibility: All you need is a valid Trintellix prescription. You’re still eligible for SingleCare discounts if you’re insured, but SingleCare discounts can’t be combined with insurance copays. 
• Get started: Choose your pharmacy from the free SingleCare Trintellix coupon page. You can enter your zip code, customize the dosage and quantity, and choose a pharmacy with the best deal. Send your virtual coupon to your phone or email, then show it to the pharmacist when you drop off your prescription.

Save up to 80% on Trintellix with SingleCare

Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.

Trintellix 20 mg (30 Tablets)

23666 - Hampton, VA

$491.07

i Price with signup

Get free coupon

$491.07

i Price with signup

Get free coupon

See Trintellix prices at all pharmacies

2. Trintellix savings card

The manufacturer of Trintellix, Takeda, offers the Trintellix savings card for commercially insured patients. Savings card holders can also use tAccess, a support program for Trintellix patients with MDD. The program provides refill reminders, informative notifications, and mobile access to the savings card.

• Best for: Patients with commercial insurance—an eligibility requirement—can benefit from a Trintellix savings card.
• Savings: Pay as little as $10 for a 30- or 90-day prescription with maximum savings of $100 for a 30-day fill or $300 for a 90-day fill. 
• Eligibility: To qualify, you must be 18 years of age or older, have commercial insurance, and have a valid Trintellix prescription. The savings card can’t be used by cash-paying patients or patients in government-funded healthcare programs, such as Medicare, Medicaid, or TRICARE. 
• Get started: Register here. Eligible patients will receive an activated online card right away. You can print the savings card or text “TSAVE” to 36395 to download it to your phone. If your healthcare provider gave you a Trintellix savings card, you can activate it using the link above. Once your card is activated, show it to your pharmacy. Call 866‑279‑0287 with questions.

3. Help at Hand patient assistance program

Takeda also offers a patient assistance program called Help at Hand.

• Best for: Patients who are uninsured or underinsured, or who demonstrate financial need, can benefit from Help at Hand. 
• Savings: This patient assistance program provides free Trintellix for eligible patients.
• Eligibility: You must meet annual household income requirements; be uninsured, underinsured, or struggling to pay for your medication; have a valid Trintellix prescription by a licensed U.S. prescriber; and reside in the United States or a U.S. territory. 
• Get started: If eligible, download this application or call 800-830-9159 to have one mailed or faxed to you. Contact your healthcare provider to start the application. Before submitting, use this checklist to ensure it’s complete.

Is there a cheaper alternative to Trintellix?

Yes, there are cheaper Trintellix alternatives, but since treatment for MDD is personalized to your needs, there’s no one-size-fits-all alternative. Trintellix is unique because it directly affects serotonin receptors, unlike other antidepressants. As a serotonin modulator and stimulator, Trintellix is an atypical antidepressant. 

SSRIs, serotonin and norepinephrine reuptake inhibitors (SNRIs), and tricyclic antidepressants are other possible treatment options.

Lea McMahon, Ed.D., chief clinical officer at Symetria Recovery, shares specific recommendations: “Prozac (fluoxetine), Wellbutrin (bupropion), Lexapro (escitalopram oxalate), and Zoloft (sertraline) are cost-effective, commonly used prescriptions to use in place of Trintellix.”

RELATED: Trintellix vs. Zoloft, Trintellix vs. Viibryd 

Remember, your healthcare provider should lead any medication changes. Don’t stop using Trintellix abruptly due to risks of serious side effects and withdrawal symptoms. In one small study, patients who stopped taking vortioxetine reported discontinuation symptoms, such as agitation, irritability, sudden worsening of mood, headaches, and nervousness. Seek advice from your healthcare provider before stopping Trintellix or switching to another medication. 

RELATED: How long does Trintellix withdrawal last? 

FAQs

How can I save the most money on Trintellix?

The three best ways to lower your Trintellix cost are:

• Using a Trintellix savings card if you have commercial insurance
• Using SingleCare Trintellix coupons for cash-paying or underinsured patients
• Applying for the Help at Hand patient assistance program if you meet income or insurance criteria

Many patients combine comparison shopping with these programs to get the lowest price.

How does the Trintellix savings card work?

The Trintellix savings card helps insured patients reduce their out-of-pocket costs. Eligible users may pay as little as $10 for a 30- or 90-day supply, depending on their prescription and insurance. After activating the card online, you simply show it to your pharmacy when filling a prescription.

Can I use a Trintellix coupon with insurance?

You can use SingleCare coupons even if you have insurance, but you cannot combine them with your insurance copay. Instead, the pharmacy can process the coupon and insurance separately, and then you can choose whichever one is cheaper.

Is there a generic version of Trintellix?

No. Trintellix is only available as a brand-name medication at this time. Since no generic vortioxetine is available, savings programs or coupons are often the most effective ways to reduce cost.

The SingleCare prices in this article are the most accurate at the time of publishing in ZIP code 23666 as of 1/20/2016. Prices vary by pharmacy. Visit our Trintellix coupon page for updated Trintellix prices near you.