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Ammonul, sodium benzoate-sodium phenylacetate
Sod Benz-Sod Phenylacet
Lowers the amount of ammonia in your blood, and keeps the amount low. Too much ammonia damages your brain and nervous system. A problem called "urea cycle disorder" causes too much ammonia in the blood.
Hyperammonemia Agent
Injectable
By injection
Injectable
Vial 50ml of 10-10%
Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
Injection routeA nurse or other health provider will give you this medicine.
You might also receive dialysis treatment with this medicine. This will help get the extra ammonia out of your blood faster.
You may also receive medicines to help prevent nausea and vomiting.
Oral routeCarefully follow your doctor's instructions about any special diet. You might need to limit how much protein you eat.
Your doctor will give you or your child a few doses of this medicine until your condition improves, and then switch you to an oral medicine that works the same way. If you have any concerns about this, talk to your doctor.
You should not receive this medicine if you have had an allergic reaction to sodium benzoate or sodium phenylacetate.
Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, congestive heart failure, edema (body swelling), low potassium in the blood, nervous system problems, or a history of seizures.
This medicine may cause unwanted effects on the nervous system. Check with your doctor right away if you or your child have lightheadedness, muscle tingling or weakness, sleepiness or unusual drowsiness, or tiredness.
Check with your doctor right away if you or your child have more than one of the following symptoms while receiving this medicine: confusion; deep or fast breathing with dizziness; muscle tremors; nausea; numbness of the feet, hands, and around the mouth; rapid, deep breathing; restlessness; stomach cramps; or unusual tiredness or weakness.
Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments. Blood tests may be needed to check for unwanted effects.
Confusion, headache, or trouble thinking clearly.
Dry mouth, increased thirst, muscle cramps, nausea, or vomiting.
Increased thirst or hunger.
Lightheadedness, dizziness, or fainting.
Numbness and tingling in your hands, feet, and around the mouth.
Seizures.
Shortness of breath or troubled breathing.
Unusual bleeding or bruising.
Unusual tiredness or weakness.
Make sure your doctor knows if you are also using probenecid (Benemid®), valproic acid (Depakene®), medicine to treat an infection (such as amoxicillin, amoxicillin/clavulanate, penicillin, Amoxil®, Augmentin®, Trimox®, or Veetids®), or a steroid medicine (such as dexamethasone, prednisolone, prednisone, or Medrol®).
This medicine may cause unwanted effects on the nervous system. Check with your doctor right away if you or your child have lightheadedness, muscle tingling or weakness, sleepiness or unusual drowsiness, or tiredness.
Check with your doctor right away if you or your child have more than one of the following symptoms while receiving this medicine: confusion; deep or fast breathing with dizziness; muscle tremors; nausea; numbness of the feet, hands, and around the mouth; rapid, deep breathing; restlessness; stomach cramps; or unusual tiredness or weakness.
Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments. Blood tests may be needed to check for unwanted effects.
Serious Side Effects
Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Burning, redness, swelling, or pain when the needle is placed.
Change in how much or how often you urinate, or painful urination.
Dry mouth, increased thirst, muscle cramps, nausea, or vomiting.
Numbness and tingling in your hands, feet, and around the mouth.
Increased thirst or hunger.
Seizures.
Unusual tiredness or weakness.
Shortness of breath or troubled breathing.
Chest pain.
Unusual bleeding or bruising.
Lightheadedness, dizziness, or fainting.
Confusion, headache, or trouble thinking clearly.
Less Serious Side Effects
Diarrhea.
Feeling anxious, nervous, or restless.
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